Accomplishments - August, 2022

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Bridget Lescelius, associate lecturer, School of Journalism and Advertising, was recently appointed lieutenant governor of the American Advertising Federation District 6. The six-year term will include serving a year as governor and organization chair. In her current role she will be in charge of social media and website development. The district comprises 13 affiliate local professional advertising clubs in Indiana, Illinois and Michigan.

Matthew Young, assistant professor, biochemistry and molecular biology, recently co-authored “Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I subunit expression, and mtDNA replication” in the August 2022 issue of the Journal of Biological Chemistry. Members of the Young lab from SIU include Carolyn Young, researcher, and Mostafijur Rahman, graduate assistant, in collaboration with Jaakko Pohjoismäki and Steffi Goffart from the Department of Environmental and Biological Sciences at the University of Eastern Finland. The research team used CRISPR gene editing to engineer a human cell line model containing a mitochondrial disease mutation. They showed that mutant cells had increased sensitivity to a mitochondrial toxicant. According to Young, this cell line is a new and essential tool that his lab will use to identify hard-to-detect toxicants and therapeutics to treat mitochondrial dysfunction. 


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